With City keeping a cleansheet against West Ham last time out, the any-time goal scorer market for Tottenham also looms as an attractive prospect.
Kane ($2.88), Erik Lamela ($4.50) and Lucas Moura ($4.50) are at the shortest odds but new signing Tanguy Ndombele ($10) could be worth a punt considering he struck in his Premier League debut last weekend.
The Red Devils struggled against Nuno Espirito’s side last season and are therefore valued at $2.20 to win away on Tuesday.
Wolves started the season with a frustrating 0-0 draw against Leicester and also must contend with a mid-week Europa League qualifier.
Marcus Rashford scored twice for United against the Blues and now leading the line, his odds of scoring anytime against Wolves ($2.75) are hard to resist.
Combine a United win with Rashford scoring anytime and throw in over 2.5 goals being scored and you’ve suddenly got a multi worth $5.75 across three legs.
Still without a competitive win under Frank Lampard, Chelsea are a side worth steering clear of right now as they look to find their feet under their new manager.
While the game will be played at Stamford Bridge, putting money on Chelsea right now is a gamble potentially not worth taking.
Odds correct at the time of publish. Please gamble responsibly. Check out the latest football odds at Sportsbet.